江仲平 男 医学博士 副教授 硕士生导师
2022年1月通过高层次人才引进到永利集团88304官网工作
邮箱:jiangzhongping0113@163.com
1.教育背景
2019.07-2021.07, 南方医科大学, 永利集团88304官网, 博士后
2013.09-2019.06, 暨南大学(硕博连读), 中药化学, 博士
2009.09-2013.06, 湖北中医药大学, 制药工程, 学士
2.教学情况
药学研究实验
3.科研情况
致力于海洋药物先导化合物的发现,在红树植物萜类和海洋甲藻超级碳链化合物的快速发现、结构鉴定和药理活性评价方面积累了丰富的经验。近五年科研成果突出,以第一作者或共同第一作者在Chemical Science、Organic Chemistry Frontiers和Bioorganic Chemistry等杂志发表SCI论文6篇,参与国自然基金重点项目和国际合作项目2项。
4.研究领域
聚焦南海特有的药用海洋生物资源(微生物、动物、植物)和海南特色南药(黎药)挖掘抗感染、抗病毒、抗AD以及治疗代谢类疾病的药物先导化合物。
5.代表性科研项目
国家自然科学基金青年基金项目,红树植物海漆来源的甘遂烷型FXR激动剂发现、结构优化及其抗NASH活性研究,2023.01-2025.12,30万,主持
6.代表性成果
1)Zhong-Ping Jiang,# Shi-Hao Sun,# Yi Yu, Attila Mándi, Jiao-Yang Luo, Mei-Hua Yang, Tibor Kurtán,* Wen-Hua Chen,* Li Shen,* and Jun Wu*. Discovery of benthol A and its challenging stereochemical assignment: opening up a new window for skeletal diversity of super-carbon-chain compounds. Chem. Sci., 2021, 12, 10197–10206. (IF = 9.825, 中科院大类一区)
2)Jun Wu,# * Zhong-Ping Jiang, # Ren-Jie Yan, Shi-Hao Sun, Yi Yu and Li Shen* Gibbosolide A, a highly functionalized 20-membered macrolide with a terminal cis-fused 2-methylhexahydro-2H-furo[3,2-b]pyran motif: insights into late-stage cyclization of marine macrolides.Org.Chem.Front., 2021, 8, 5756–5765. (IF = 5.281, 中科院大类一区)
3)Zhong-Ping Jiang, Yi Yu, Li Shen.* Agallolides A-M, including two rearranged ent-atisanes featuring a bicyclo[3.2.1]octane motif, from the Chinese Excoecaria agallocha. Bioorg. Chem., 2020, 104: 104206; doi: 10.1016/j.bioorg.2020.104206. (IF = 5.275)
4)Zhong-Ping Jiang#, Zhi-Lin Luan#, Ruo-Xi Liu, Qun Zhang, Xiao-Chi Ma, Li Shen,* and Jun Wu.* Mangrove Tirucallane-and Apotirucallane-Type Triterpenoids: Structure Diversity of the C-17 Side-Chain and Natural Agonists of Human Farnesoid/Pregnane–X–Receptor. Mar. Drugs., 2018, 16(12), 488; doi:10.3390/md16120488. (IF = 4.073)
5)Zhong-Ping Jiang, Bin-Hua Zou, Xiao-Juan Li, Jun-Jun Liu, Li Shen,* Jun Wu.* Ent-kauranes from the Chinese Excoecaria agallocha L. and NF-κB inhibitory activity. Fitoterapia, 2019, 133, 159–170. (IF = 2.527)
6)Zhong-Ping Jiang, Li-Wen Tian, Li Shen,* Jun Wu.* Ent-abietanes from the Godavari mangrove, Ceriops decandra: Absolute configuration and NF-κB inhibitory activity. Fitoterapia, 2018, 130, 272–280. (IF = 2.527)
7)Wanshan Li, Zhongping Jiang, Li Shen,* Patchara Pedpradab, Torsten Bruhn, Jun Wu,* and Gerhard Bringmann.* Antiviral Limonoids Including Khayanolides from the Trang Mangrove Plant Xylocarpus moluccensis. J. Nat. Prod., 2015, 7, 1570–1578. (IF = 3.779)
欢迎具有药学、化学、生物学背景的同学报考本课题组研究生。